Anti-depressants and Surgery

By Health Day

Selective serotonin reuptake inhibitors or SSRI's. are among the most commonly prescribed medications in the United States.

Now, new research, just published in the Journal of the American Medical Association, suggests taking these antidepressants before surgery may increase the risk of adverse outcomes.

The study looked at more than 5-hundred-30 thousand patients over the age of 18...who had major surgery during a two-year span from 2006 to 2008. More than 72,000 had received an SSRI during their hospitalization (Cindy, I was trying not to say perioperative period because people won't know what that is, but I'm not sure during the hospitalization works. Thoughts?).

Researchers analyzed data on length of stay, readmission, bleeding events, heart issues and death after surgery.

After adjusting for factors such as obesity, pulmonary disease and depression, the data showed that patients on SSRIs before surgery had higher odds of bleeding, readmission and in-hospital mortality.

The researchers say further study is needed to determine if other patient factors or the SSRIs themselves are responsible.

I'm Dr. Cindy Haines of HealthDay TV with the news that can help you stay healthy, happy, and fit.

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